d020 <- read.table(here::here("data", "EPILEPSY.txt"), header = TRUE)D020. Treatment vs. placebo on the number of epileptic seizures
The data file can be downloaded here:
This dataset is from a clinical trial that was investigating the effect of a new treatment for epilepsy (trt; active treatment and placebo) involving 59 patients (patient). The number of epileptic seizures was counted over an 8-week period prior to treatment as baseline (base), and then following the treatment (seizure) over four 2-week periods (time). A logarithmic transformation (lbase) was performed over the baseline data (Brown and Prescott 2006).
| patient | time | trt | seizure | base | lbase |
|---|---|---|---|---|---|
| 1 | 1 | 0 | 5 | 11 | 2.3979 |
| 1 | 2 | 0 | 3 | 11 | 2.3979 |
| 1 | 3 | 0 | 3 | 11 | 2.3979 |
| 1 | 4 | 0 | 3 | 11 | 2.3979 |
| 2 | 1 | 0 | 3 | 11 | 2.3979 |
| 2 | 2 | 0 | 5 | 11 | 2.3979 |
| 2 | 3 | 0 | 3 | 11 | 2.3979 |
| 2 | 4 | 0 | 3 | 11 | 2.3979 |